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Home
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Target
Enzymes
Transferase
Histone methyltransferase (HMTs)

Histone methyltransferase (HMTs)

6 Items

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Histone methyltransferase (HMTs)

Sort By Set Descending Direction

BIX 01294 (HB1413)

Description:
Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.

Purity:
>98%

Pack:
10mg

Price:

$215

Qty:

Pack:
50mg

Price:

$751

Qty:

Supporting Docs Add to Favorites
Chaetocin (HB1415)

Description:
Potent histone methyltransferase SUV39H1 inhibitor

Purity:
>99%

Pack:
1mg

Price:

$226

Qty:

Pack:
5mg

Price:

$912

Qty:

Supporting Docs Add to Favorites
Daminozide (HB1404)

Description:
Selective KDM2/7 histone demethylase inhibitor

Pack:
100mg

Price:

$151

Qty:

Pack:
500mg

Price:

$609

Qty:

Supporting Docs Add to Favorites
3-Deazaneplanocin A hydrochloride (HB1416)

Description:
Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.

Purity:
>98%

Pack:
500μg

Price:

$123

Qty:

Pack:
1mg

Price:

$180

Qty:

Pack:
5mg

Price:

$812

Qty:

Supporting Docs Add to Favorites
UNC 0224 (HB1420)

Description:
Potent, selective G9a HMTase inhibitor

Purity:
>98%

Pack:
10mg

Price:

$211

Qty:

Pack:
50mg

Price:

$815

Qty:

Supporting Docs Add to Favorites
UNC 0646 (HB1423)

Description:
Potent, selective G9a / GLP HMTase inhibitor

Purity:
>99%

Pack:
10mg

Price:

$217

Qty:

Pack:
50mg

Price:

$854

Qty:

Supporting Docs Add to Favorites

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      1. Group I (mGlu₅, mGlu₁)(21)
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    12. GABA-B(9)
      1. Miscellaneous(1)
    13. Histamine(9)
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      2. H₂(2)
      3. Non-selective(1)
    14. Leukotriene(1)
      1. LTD4(1)
    15. Lysophosphatidic Acid(1)
      1. Non-selective(1)
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    17. Peptide Receptors(39)
      1. AdipoR(4)
      2. Angiotensin(3)
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        Non-selective(2)
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      6. Glucagon and related(3)
        GLP-1(1)
      7. Ghrelin(1)
      8. Mas-Related G Protein-Coupled Receptors (MRGPRS)(1)
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        OX1(4)
        OX2(5)
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      14. Protease-Activated Receptors (PAR)(4)
      15. Somatostatin (SST)(1)
      16. Tachykinin(1)
      17. Galanin(2)
    18. Purinergic: P2Y(3)
      1. P2Y₆(1)
      2. P2Y₁₂(1)
    19. 5-HT(45)
      1. 5-HT₁(17)
        5-HT_1A(8)
        5-HT_1B(5)
        5-HT_1C(1)
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        Non-selective(2)
      3. 5-HT₄(3)
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      7. Other(3)
    20. Sphingosine-1-phosphate(2)
    21. Smo(4)
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      1. TGF-β(7)
      2. BMP/Activin(2)
    2. RTK(17)
      1. CSF1R (Colony stimulating factor 1 receptor)(3)
      2. FGFR(2)
      3. VEGFR(1)
      4. Trk receptors(9)
      5. Eph(1)
    3. Toll-like receptor(6)
      1. TLR2(1)
      2. TLR7(3)
  3. Nuclear Receptors(43)
    1. Aryl hydrocarbon receptor(1)
    2. Estrogen and related(16)
      1. Estrogen-α(2)
      2. Estrogen-β(2)
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    3. Liver X and farnesoid X receptors (LXR/FXR)(2)
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      1. DAF-12(1)
      2. Ecdysone receptor(4)
    7. PPAR(9)
      1. PPARγ(9)
      2. PPARδ(1)
    8. Progesterone(1)
    9. Retinoic Acid (RAR)(1)
  4. Transporters(36)
    1. Cannabinoid(1)
    2. Dopamine (DAT)(1)
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    6. Monoamine(2)
      1. VMAT2(1)
    7. Multidrug Transporters(1)
    8. Na⁺/Ca²⁺ exchangers(2)
    9. Na⁺/H⁺ exchangers(1)
    10. 5-HT uptake & transport(15)
    11. SGLT(1)
      1. SGLT-2(1)
    12. Norepinephrine (NET)(2)
  5. Other(2)
    1. σ(1)
      1. σ1(1)
    2. Imidazoline Receptors(1)
      1. Imidazoline I₂(1)
2. Ion channels(238)
  1. Ligand-gated ion channel(126)
    1. Ionotropic glutamate receptors(84)
      1. AMPA(27)
      2. NMDA(40)
        GluN1(3)
        GluN2(5)
        GluN2A(2)
        GluN2B(2)
        GluN2C(4)
        GluN2D(4)
      3. Kainate(16)
      4. Miscellaneous(9)
      5. Non-selective ionotropic glutamate(2)
    2. Purinergic: P2X(7)
      1. P2X₄(1)
      2. P2X₇(1)
      3. Non-selective(3)
    3. Acid-sensing (proton-gated) (ASICs)(1)
    4. GABA-A(21)
    5. IP₃(2)
    6. Glycine(3)
    7. Nicotinic AcH(8)
      1. α3β4(1)
      2. α4β2(1)
      3. α7(4)
      4. Non-selective(2)
    8. PSEMS(4)
    9. 5-HT₃(1)
  2. Voltage-gated ion channel(107)
    1. Sodium Channels(17)
    2. Potassium Channels(48)
      1. Voltage-gated (K_v)(14)
      2. Two-P(7)
      3. BK channels(3)
      4. Calcium activated (K_Ca)(14)
      5. Inwardly rectifying (K_ir)(10)
    3. Ryanodine receptor(1)
      1. Non-selective(1)
    4. Calcium Channels(20)
      1. Ca_v1.x (L-type) (7)
      2. Ca_v2.x(7)
      3. Ca_v3.x (T-type)(3)
    5. Cyclic nucleotide-regulated channels(2)
    6. TRP(21)
      1. TRPA(3)
      2. TRPC(2)
        TRPC6(1)
      3. TRPM(4)
      4. TRPV(10)
  3. Other(9)
    1. Ionophores(3)
    2. Piezo(6)
3. Enzymes(385)
  1. ATPase / GTPase(16)
    1. Ca²⁺-ATPase (SERCA)(5)
    2. H⁺-ATPase(5)
    3. Myosin ATPase(3)
      1. Na⁺/K⁺ ATPase(2)
  2. Cyclase(5)
    1. Adenylyl cyclase(2)
    2. Guanylyl cyclase(3)
  3. Deacetylase(19)
    1. Histone deacetylase (HDAC)(19)
      1. Non-selective(2)
      2. Sirtuin(2)
        SIRT2(1)
        Sir2P(1)
  4. Deaminase(2)
    1. XMP aminase(1)
  5. Demethylase(4)
    1. Histone demethylase(4)
  6. Dehydrogenase(3)
    1. Aldehyde Dehydrogenase(1)
    2. Monophosphatase dehydrogenase(1)
  7. Esterase(10)
    1. Lipase(1)
    2. Phospholipase(3)
  8. Glycosylase(2)
    1. Glucosidase(2)
      1. α(2)
  9. Hydrolase(4)
    1. FAAH(2)
    2. GCH1 (GTP cyclohydrolase I)(1)
    3. Helicase(1)
  10. Hydroxylase(5)
    1. Tryptophan hydroxylase(1)
    2. Tyrosine Hydroxylase(3)
  11. Isomerase(11)
    1. DNA Topoisomerase(11)
      1. DNA Gyrase(1)
      2. Type 1(3)
      3. Type 2(6)
  12. Kinase(143)
    1. Abl(1)
    2. Akt / PKB(5)
    3. AMPK(5)
    4. Aurora kinase(5)
      1. Aurora Kinase A(2)
      2. Aurora Kinase B(1)
      3. Non-selective(1)
    5. BTK(1)
    6. CAM Kinase II(4)
    7. Casein kinase(4)
    8. CDK(3)
      1. CDK1(3)
      2. CDK2(1)
      3. Non-selective(3)
    9. c-Src(5)
    10. DYRK(1)
    11. ERK(2)
      1. ERK2 / MAPK1(1)
    12. GRK(4)
      1. Non-selective(1)
    13. GSK-3(8)
    14. Hexokinase(1)
    15. JAK(5)
    16. MAPK(15)
      1. p38 MAPK(8)
      2. MEK(5)
        MEK1(1)
      3. JNK(2)
    17. MAPKAP(1)
      1. MAPKAP2(1)
    18. mTOR(5)
    19. Myosin light chain kinase (MLCK)(1)
    20. Non-selective(2)
    21. PERK(1)
    22. PKA(5)
    23. PKC(32)
    24. PKG(2)
    25. PI-3K(6)
    26. Protein-serine/threonine kinase(3)
    27. Protein-tyrosine kinase(2)
      1. Non-selective(2)
    28. RIP kinase(3)
      1. RIP1(2)
    29. ROCK(7)
    30. RSK(1)
    31. Sphingosine kinase(1)
    32. Syk(1)
    33. Raf(2)
      1. B-Raf(2)
      2. c-RAF(2)
  13. Ligase(1)
    1. Ubiquitin/Ubl E2 conjugating(1)
      1. Ub-conjugating enzyme (E2) complex(1)
  14. Oxidase(4)
    1. Monoamine Oxidase(2)
      1. Non-selective(2)
    2. Tyrosinase(1)
  15. Oxygenase(8)
    1. COX(6)
      1. COX-2(2)
    2. 5-lipoxygenase(2)
  16. Phosphodiesterase(10)
    1. PDE1(4)
    2. PDE4(4)
    3. Non-selective(2)
    4. Sphingomyelinase(1)
      1. N-Smase(1)
  17. Phosphatase(25)
    1. Alkaline phosphatase(2)
    2. Protein-tyrosine phosphatase(7)
      1. PTP1B(1)
  18. Polymerase(9)
    1. DNA/RNA(5)
    2. Tankyrase (TNKS)(2)
    3. Telomerase(2)
  19. Protease / Peptidase(55)
    1. ACE2(1)
    2. Aminopeptidase(1)
    3. Angiotensin-Converting Enzyme (ACE)(1)
    4. Aspartic protease(1)
    5. Calpains(1)
    6. Caspase(11)
      1. Broad(2)
    7. Cathepsin(1)
      1. Cathepsin B(1)
    8. Deubiquitinating Enzymes(1)
      1. Ubiquitin C-terminal hydrolase(1)
    9. Dipeptidyl-peptidase 4(1)
    10. Elastase(1)
    11. Matrix metalloprotease(2)
      1. MMP-1(1)
    12. Methionine aminopeptidase-2(1)
    13. Other(4)
    14. Protease inhibitors and inhibitor cocktails(11)
    15. Prolyl endopeptidase (PREP)(1)
    16. Proteasome(12)
    17. Serine/cysteine protease(2)
    18. Secretase(4)
      1. γ(4)
  20. Reductase(3)
    1. Aldose reductase(1)
    2. NADH ubiquinone oxidoreductase(1)
  21. Synthase(14)
    1. HMG-CoA synthase(1)
  22. Transferase(36)
    1. ACAT(5)
    2. DGAT(2)
    3. DNA methyltransferase (DNMT)(4)
    4. Histone acetyltransferase (HAT)(1)
    5. Histone methyltransferase (HMTs)(6)
    6. Phosphorylase(1)
    7. Protein prenyltransferases(6)
    8. PORCN(4)
    9. Tankyrase (TNKS)(1)
4. Proteins - Other(59)
  1. Actin(8)
  2. Choline ester transfer protein (CETP)(1)
  3. GAPDH(1)
  4. GFAP(4)
  5. GFP(3)
  6. Histones(5)
    1. Bromodomain(4)
  7. HSP60(1)
  8. MAP2(2)
  9. mCherry(1)
  10. NeuN(3)
  11. Neurofilament L(1)
  12. Neurofilament M(1)
  13. N-WASP(1)
  14. Plasminogen PAI-1(1)
  15. STAT(5)
  16. Tubulin(4)
    1. βIII-tubulin(2)
    2. β-tubulin(1)
  17. Myelin basic protein(1)
  18. c-Fos(1)
  19. IBA1(1)
  20. Alpha-synuclein(1)
  21. VLP1(1)
Cell signaling
1. PI3K/Akt/mTOR(17)
  1. Akt(5)
  2. PI3K(6)
  3. mTOR(5)
2. TGF-Beta/SMAD/ROCK(16)
  1. Bcr-Abl(1)
  2. ROCK(7)
  3. TGF-Beta/ SMAD(8)
3. MAPK(19)
  1. p38 MAPK(9)
  2. MEK(5)
  3. ERK(2)
    1. ERK2 / MAPK1(1)
  4. JNK(2)
  5. Raf(1)
4. Estrogen & other Nuclear Receptors(19)
  1. Aryl Hydrocarbon Receptors(1)
  2. Estrogen Receptor signaling(16)
    1. Estrogen-α(2)
    2. Estrogen-β(2)
    3. Non-selective(12)
  3. Estrogen GPER receptors(1)
  4. PPAR(2)
5. Wnt/Beta-Catenin signaling(10)
  1. β-catenin(8)
6. Anticancer(15)
  1. Cytotoxic(7)
7. Anti-oxidant(10)
  1. Mitochondrial complex II(2)
8. Cyclic nucleotide and related(44)
  1. Adenylyl cyclase (AC)(2)
  2. cAMP(3)
  3. Guanyl cyclase (GC)(2)
  4. Inositol trisphosphate (IP3)(2)
  5. PKA(5)
  6. PKC(31)
9. Ca²⁺ signaling(29)
10. Gap channels (gap junctions)(3)
11. G protein(6)
  1. Small monomeric GTPase(2)
  2. G Protein (Heterotrimeric)(4)
12. Heatshock proteins(3)
  1. HSP90(3)
13. Hedgehog signaling(10)
14. Immune Checkpoint(3)
15. Lipid signaling(1)
16. Notch(4)
17. Transcription factors(9)
  1. HIF(1)
  2. NFAT(3)
  3. NGF(1)
  4. Stats(4)
Cell process
1. COVID-19 Research(191)
  1. Compound repurposing(36)
  2. Virus attachment / entry(10)
    1. TMPRSS2(1)
    2. ACE2(3)
    3. Endocytosis(6)
  3. Virus replication, transcription & maturation(16)
  4. Cytokine Storm / Immune response signaling(78)
    1. Angiotensin related(3)
    2. Cytokines, chemokines & NF-κB/I-κB(20)
      1. Chemokine Receptors(2)
      2. Cytokine Stimulation/ Production(10)
      3. NF-κB / IκB(8)
    3. Inflammasomes(6)
    4. JAK/STAT(9)
    5. MAPK Signaling(18)
      1. p38 MAPK(8)
      2. MEK(5)
      3. ERK(2)
        ERK2 / MAPK1(1)
      4. JNK(2)
      5. Raf(1)
    6. PI3K/Akt/mTOR(15)
      1. Akt(4)
      2. PI3K(6)
      3. mTOR(5)
    7. Protease-Activated Receptors(3)
    8. TLR (Toll-like receptors) signaling(6)
      1. TLR2(1)
      2. TLR7(3)
  5. Organoids(13)
  6. Cell culture reagents & buffers(44)
    1. Selection Antibiotics(8)
    2. Protease inhibitor cocktails and inhibitors(12)
  7. Cell stains, viability & proliferation(13)
  8. CRISPR/ Gene editing(13)
2. Apoptosis & cell cycle(48)
  1. Caspase(11)
  2. Inducers(13)
  3. p53(2)
  4. PARP(4)
    1. PARP-1(2)
    2. Non-selective(1)
  5. RIP kinase(1)
  6. Stains(13)
3. Cell Metabolism(75)
  1. Autophagy(11)
  2. Amyloid-β(12)
  3. Bioactive metabolites(3)
  4. DNA / RNA & protein synthesis(34)
    1. Genome editing / engineering(9)
  5. Oxidative Phosphorylation(5)
  6. Ubiquitin-proteasome system (UPS) (12)
4. Cytoskeleton and Extracellular Matrix(35)
  1. Actin(7)
  2. Matrix Metalloproteases (MMP)(3)
  3. Microtubule(5)
  4. ROCK (Rho-kinase)(7)
5. Immunology & Inflammation(176)
  1. Antivirals / Antibiotics / immunomodulators(143)
    1. Antibiotics(81)
    2. Antimicrobials(9)
    3. Antivirals(28)
      1. COVID-19/SARS-CoV-2 related(19)
    4. Immunosupressants / immunomodulators(10)
    5. Mycotoxin(4)
    6. T-cell Related(9)
  2. Cytokines, chemokines & NF-κB/I-κB(23)
    1. Chemokine Receptors(3)
    2. Cytokine Stimulation/ Production(10)
    3. JNK(2)
    4. NF-κB / IκB(8)
  3. Inflammasome(6)
  4. JAK/STAT(9)
  5. TLR (Toll-like receptors)(6)
    1. TLR2(1)
    2. TLR7(3)
    3. Non-selective(2)
6. Oxidative Stress(7)
  1. ROS(3)
  2. NOS(4)
7. Stem cells(112)
  1. Dedifferentiation(6)
  2. Differentiation(59)
    1. iPSCs & ESCs(18)
    2. Mesenchymal Stem cells (MSCs)(11)
    3. Neural Stem Cells (NSCs)(30)
      1. Neurotrophins(5)
  3. Organoids(14)
  4. Proliferation, self-renewal, maintenance(29)
  5. Reprogramming(22)
  6. Stem cell signaling(20)
8. Epigenetics(4)

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