My Cart
My account
Menu
Main Menu

Wortmannin

(HB2778)
Be the first to add a publication

Certificate of Analysis

Latest Certificate of Analysis

Download the latest CoA for this product:

Download CoA

Download Batch-Specific CoA

To download the CoA for a batch, enter the batch ID below:

Technical documents: CoA SDS Datasheet
1  Review
Top Reviews:
100% of 100
Add Your Review
Add to Wish List

Product overview

Name Wortmannin
Alternative names SL-2052
Purity >99%
Description Potent, selective, irreversible PI3-K inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews (1) References (3)
Write Your Own Review
You're reviewing:Wortmannin
Rate this item:

Biological Data

Biological description Potent, selective, non-compettive and irreversible PI3-K inhibitor (IC50 = 2-4 nM). Also inhibits PI3-K related kinases and PLK1. Cell permeable. Shows variety of biological actions.

Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview DMSO (50mM) and Ethanol (5mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >99%
Chemical name (1S,6bR,9aS,11R,11bR) 11-(Acetyloxy)-1,6b,7,8,9a,10,11,11 b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-f uro[4,3,2-de]indeno[4,5,-h]-2-h]-2-benzopyran-3,6, 9-trione
Molecular Weight 428.44
Molecular Formula C23H24O8
CAS Number 19545-26-7
PubChem identifier 3003565
SMILES O=C(C4=CO5)O[C@H](COC)[C@@]1(C)C4=C5C(C2=C1[C@H](OC(C)=O)C[C@@]3(C)C2CCC3=O)=O
InChiKey QDLHCMPXEPAAMD-ZGSWIPFCSA-N

References for Wortmannin

References are publications that support the biological activity of the product

  • Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.

    Liu et al (2005) Chem Biol 12(1) : 99-107
    Read more (PubMedID: 15664519)

  • Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

    Ui et al (1995) Trends Biochem Sci 20(8) : 303-7
    Read more (PubMedID: 7667888)

  • Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.

    Powis et al (1994) Cancer Res 54(9) : 2419-23
    Read more (PubMedID: 8162590)

3 Item(s)

Related Products
Grouped product items
Order: HB2778
Pack Price Qty
1mg
$79
5mg
$257
10mg
$475
Potent, selective, irreversible PI3-K inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@m2stage-v2.hellobio.com

Related Products

LY 294002 hydrochloride
Code:
HB2266
Pack:
5mg, 25mg
Price:
$57, $184
(Free trial)
PI3-K inhibitor. Suppresses mESC proliferation.
PD 98059
Code:
HB2244
Pack:
1mg, 10mg, 50mg
Price:
$48, $103, $462
(Free trial)
Selective MEK1/MAP2K inhibitor. Enhances ESC self-renewal.
U0126
Code:
HB2246
Pack:
1mg, 5mg, 25mg
Price:
$66, $171, $708
(Free trial)
Potent, selective MEK-1/MEK-2 inhibitor