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Biological Data
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Biological description
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Broad spectrum antibiotic which binds to the 30S subunit of the bacterial ribosome to inhibit protein synthesis.
Widely used as a selection marker for cells transformed with kanamycin B resistance gene. |
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Application notes
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- Used at 50µg/ml to selectively culture E. coli transfected with plasmids conferring kanamycin resistance
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Solubility & Handling
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Storage instructions
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Room temperature |
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Solubility overview
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Soluble in water (75 mM) |
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Important
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This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
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Chemical name
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(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-bis(azanyl)-3-[(2S,3R,4S,5S,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-2-oxidanyl-cyclohexyl]oxy-oxane-3,4,5-triol sulphate |
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Chemical structure
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![Kanamycin sulfate [25389-94-0] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Kanamycin sulfate [25389-94-0]")
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Molecular Formula
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C18H36N4O11 .H2O4S |
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PubChem identifier
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441374 |
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SMILES
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C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N.OS(=O)(=O)O |
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InChi
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InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1 |
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InChiKey
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QRRMITCICIMIDC-UHFFFAOYSA-N |
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Appearance
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White to off-white |
References for Kanamycin sulfate
References are publications that support the biological activity of the product
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The Effect of Kanamycin and Tetracycline on Growth and Photosynthetic Activity of Two Chlorophyte Algae
Bashir et al (2016)
Biomed Res Int. : 5656304
Protein synthesis inhibitor. Broad spectrum antibiotic.
![Kanamycin sulfate [25389-94-0] Chemical Structure](https://m2stage-v2.hellobio.com/media/catalog/product//h/b/hb4429.png "Kanamycin sulfate [25389-94-0]")
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