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Biological Data
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Biological description
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RNA polymerase inhibitor and RNA synthesis inhibitor. DNA intercalating agent. Shows antitumor and cytotoxic effects. Also induces apoptosis. |
Solubility & Handling
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Storage instructions
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+4°C |
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Solubility overview
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Soluble in DMSO (50 mM) |
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Important
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This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
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Chemical name
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2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
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Molecular Formula
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C62H86N12O16 |
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SMILES
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CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C |
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InChiKey
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RJURFGZVJUQBHK-LIAOQTPJSA-N |
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Appearance
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Red shiny crystals |
RNA polymerase inhibitor. Apoptosis inducer.
Understanding purity and quality - a guide for life scientists 
