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Biological Data
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Biological description
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Selective ROCK (Rho-kinase) inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). |
Solubility & Handling
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Storage instructions
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+4°C |
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Solubility overview
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Soluble in DMSO (100mM) or ethanol (25mM) |
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Important
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This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
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Chemical name
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4-[4-(Trifluoromethyl)phenyl]-N-(6- Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tet rahydro-3-pyridinecarboxamide |
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Molecular Formula
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C21H16F4N4O2 |
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PubChem identifier
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11373846 |
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SMILES
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O=C1CC(C2=CC=C(C(F)(F)F)C=C2)C(C(NC3=C(F)C=C(NN=C4)C4=C3)=O)=C(C)N1 |
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InChiKey
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OLIIUAHHAZEXEX-UHFFFAOYSA-N |