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Biological Data
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Biological description
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Potent, selective ROCK inhibitor (IC50 value = 11.8 nM). Glycyl analog of the ROCK inhibitor H 1152 dihydrochloride. |
Solubility & Handling
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Storage instructions
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room temperature (desiccate) |
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Solubility overview
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Soluble in water (100mM) or DMSO (50mM) |
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Important
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This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
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Chemical name
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(S)-(+)-4-Glycyl-2-methyl-1-[(4-met hyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-dia zepine dihydrochloride |
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Molecular Formula
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C18H24N4O3S.2HCl |
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PubChem identifier
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56972177 |
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SMILES
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CC1=CN=CC2=C1C(S(N3CCCN(C(CN)=O)C[C@@H]3C)(=O)=O)=CC=C2.Cl.Cl |
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InChiKey
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ILDBNQGLZFSHQZ-UTLKBRERSA-N |
Potent, selective ROCK inhibitor
Understanding purity and quality - a guide for life scientists