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Biological Data
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Biological description
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Selective serotonin reuptake inhibitor and σ1 receptor agonist (Ki = 36 nM at σ1). Shows antidepressant and anxiolytic activity. Active in vivo. |
Solubility & Handling
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Storage instructions
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+4°C (desiccate) |
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Solubility overview
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Soluble in water (10mM) |
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Important
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This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
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Chemical name
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(E)-5-Methoxy-1-[4-(trifluoromethyl )phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate |
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Chemical structure
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![Fluvoxamine maleate [61718-82-9] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Fluvoxamine maleate [61718-82-9]")
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Molecular Formula
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C15H21F3N2O2.C4H4O4 |
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PubChem identifier
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9560989 |
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SMILES
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COCCCC/C(=N\OCCN)/C1=CC=C(C=C1)C(F)(F)F.C(=C\C(=O)O)\C(=O)O |
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InChi
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InChI=1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1- |
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InChiKey
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LFMYNZPAVPMEGP-PIDGMYBPSA-N |
References for Fluvoxamine maleate
References are publications that support the biological activity of the product
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Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain.
Narita et al (1996)
Eur J Pharmacol 307(1) : 117-9
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Fluvoxamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness.
Benfield (1986)
Drugs 32(4) : 313-34
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Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor.
Claassen et al (1977)
Br J Pharmacol 60(4) : 505-16
Selective serotonin reuptake inhibitor and σ1 receptor agonist
![Fluvoxamine maleate [61718-82-9] Chemical Structure](https://m2stage-v2.hellobio.com/media/catalog/product//h/b/hb2138.png "Fluvoxamine maleate [61718-82-9]")
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