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Biological Data
Biological description
PD-1/PD-L1 interaction inhibitor (Kd = 0.51µM at PD-L1). Inhibits tumor growth and prolongs survival time of mice in vivo.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in water (2 mg/ml)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data
Molecular Formula
C70 H98 N20 O21
References for (D)-PPA 1
References are publications that support the biological activity of the product
PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer.
Sun Z et al (2018)
Drug delivery 25 : 1746-1755
Blocking of the PD-1/PD-L1 Interaction by a D-Peptide Antagonist for Cancer Immunotherapy.
Chang HN et al (2015)
Angewandte Chemie (International ed. in English) 54 : 11760-4
PD-1/PD-L1 interaction inhibitor
Understanding purity and quality - a guide for life scientists 
